Although there is no single cause for infant colic, undigested lactose in food as a result of Transient Lactase Deficiency has been identified as a causative factor in many babies suffering from colic. Comparative research of six alternative approaches to the treatment of colic symptoms in babies has shown that while other options offered some relief, only pre-incubation of baby milk with a lactase enzyme such as Colief Infant Drops dramatically reduced the crying time in seriously colicky babies. Suitable for breast and bottle-fed babies.